Latest Publication
A subcellular proteome atlas of the yeast Komagataella phaffii. (2020) Valli M, Grillitsch K, Grünwald-Gruber C, Tatto NE, Hrobath B, Klug L, Ivashov V, Hauzmayer S, Koller M, Tir N, Leisch F, Gasser B, Graf AB, Altmann F, Daum G, Mattanovich D. FEMS Yeast Res. 2020 Feb 1;20(1). pii: foaa001. doi: 10.1093/femsyr/foaa001.
BOKU Invention Award 2019 for Brigitte Gasser, Diethard Mattanovich, Michael Sauer and Thomas Gaßler
The inventors, Diethard Mattanovich, Brigitte Gasser, Michael Sauer and Thomas Gaßler were able to convince the jury with the "CarboFeed" technology. In this project, a method was developed that makes it possible to process CO2 into an animal feed additive by using a novel yeast. The aim is using CO2 as a sustainable source of raw materials and it also has the eco-friendly effect that no further agricultural land is needed for the production of animal feed.
New Publication
The secretome of Pichia pastoris in fed-batch cultivations is largely independent of the carbon source but changes quantitatively over cultivation time.
Burgard J, Grünwald-Gruber C, Altmann F, Zanghellini J, Valli M, Mattanovich D, Gasser B. (2019) Microb Biotechnol. 2019 Nov 6. doi: 10.1111/1751-7915.13499.
OeGMBT Life Science PhD Award for Thomas Gaßler
At the Life Science Conference of the Austrian Society for Molecular Biosciences and Biotechnology (ÖGMBT), young scientists were honoured for their internationally sensational work - including Thomas Gaßler (DBT) with his work on the biotechnological use of CO2.
Diethard Mattanovich re-elected Vice-President of the European Federation of Biotechnology (EFB).
At the last meeting of the Executive Board of the European Federation of Biotechnology in Barcelona, Diethard Mattanovich was re-elected Vice-President of the European Federation of Biotechnology (EFB).
Latest Publication
A single Gal4-like transcription factor activates the Crabtree effect in Komagataella phaffii
Ata Ö, Rebnegger C, Tatto NE, Valli M, Mairinger T, Hann S, Steiger MG, Çalık P, Mattanovich D.
Nature Communications, 9:4911 doi: 10.1038/s41467-018-07430-4
New Publication in Nature Biotech
The industrial yeast Pichia pastoris is converted from a heterotroph into an autotroph capable of growth on CO2. (2019) Gaßler, T., Sauer M., Gasser B., Egermeier M., Troyer Ch., Causon T., Hann St., Mattanovich D., Steiger M. Nature Biotechnology https://doi.org/10.1038/s41587-019-0363-0
GOLD medal for iGEM Vienna Team @Giant Jamboree 2019 in Boston
The Giant Jamboree is an annual event that showcases work from the iGEM Competition. All iGEM teams were invited to present their synthetic biology projects and compete for prizes in Boston, US.
The iGEM Vienna team participated for the third time at this event and we all are proud and happy to say that in 2019 their efforts were rewarded in form of a Gold Medal! - congratulations!
New Publication
Spotlight on biodiversity of microbial cell factories for glycerol conversion.
Russmayer H, Egermeier M, Kalemasi D, Sauer M. (2019) Biotechnol Adv 1;37(6):107395. doi: 10.1016/j.biotechadv.2019.05.001.
Book release
Recombinant Protein Production in Yeast
This volume provides an overview of the main yeast production platforms currently used and future yeast cell factories for recombinant protein production. Chapters detail approaches of genetic and metabolic engineering, co-factor containing proteins and virus-like particles, glycoproteins, and post-translational modifications of proteins.
in: Methods Mol Biol. 2019;1923: ISBN-13: 978-1493990238
Genschalter in Hefe entdeckt
Forschende am Department für Biotechnologie der Universität für Bodenkultur Wien (BOKU) und des Austrian Centre of Industrial Biotechnology (acib) haben einen Genschalter in Hefe entdeckt, der vor Jahrmillionen zwölf Gene gleichzeitig verändert und dadurch den Hefe-Stoffwechselprozess angekurbelt hat. Die in Nature Communications veröffentlichten Forschungsergebnisse bergen großes Potenzial in der Lebensmittelproduktion, der Erzeugung von Biotreibstoffen oder zur Entwicklung von Grundstoffen für Bioplastik.
Transforming CO2 into animal feed
Thomas Gaßler and Michael Egermeier were selected for a FFG Spin-Off Fellowship grant for the transformation of their project “CarboFeed” (Biotechnological production of high-value yeast based animal feed additives from CO2) together with Diethard Mattanovich.
Latest Publication
Characterization of methanol utilization negative Pichia pastoris for secreted protein production: New cultivation strategies for current and future applications. Biotechnol Bioeng. (2020) Zavec, D; Gasser, B; Mattanovich, D. Feb 8. doi: 10.1002/bit.27303.
BOKU Inventor 2019
This year the award BOKU inventor 2019 went ex aequo to Hertha Steinkellner (DAGZ), Reingard Grabherr (Head of Department of Biotechnology) and Brigitte Gasser (DBT). In addition to a cash prize, their commitment and exemplary effect will be rewarded with a personal video presented at the BOKU Autumn Festival at IFA Tulln. - Congratulations!
Rudolf Sallinger Special Award for CarboFeed
The CarboFeed team from the Department of Biotechnology was delighted to receive a special jury prize for their CO2-fixing yeast strain technology at the S&B Award 2019.
Best Student Talk Award to Dominik Jeschek -
congrats !
At the 10th ÖGMBT Annual Meeting (Ten Years Life, Science & Molecules) in Vienna, Dominik Jeschek, from acib at Department of Biotechnology, was awarded 2nd place in Best Student Talk Award for his presentation on “Phospholipid vesicles to determine the transport functionality of mitochondrial carrier proteins”.
Christian Doppler Laboratory for Biotechnology of Glycerol
The CD-Laboratory for Biotechnology of Glycerol is dedicated to the microbial valorization of crude glycerol from biodiesel production.
Christian Doppler Laboratory for Growth-Decoupled Protein Production in Yeast
A report on the CD-lab of Brigitte Gasser in the magazine "Chemiereport 2017-03" (text only available in German).
New raw material aconitic acid
Scientists at the Austrian Centre of Industrial Biotechnology (acib) succeded in using the mold fungi Aspergillus niger to produce aconitic acid - a new raw material and important building block for the production of non-toxic bioplastics. (published in: Bioplastics Magazine 06/2017, p36)